Jinhee Choi is interested in understanding the molecular mechanism of environmental chemicals-induced toxicity for protection of human and ecosystem health. She did her PhD in Eco-toxicology Lab of University of Paris-Sud (XI), Orsay, France.During her PhD, she conducted multi-bio-marker research in various lab and field scale eco-toxicology projects and identified oxidative stress bio-markers due to chemical exposure in freshwater invertebrates. After her PhD, she did postdoctoral fellowship in Seoul National University, Medical school.
While then she investigated DNA repair mechanism due to oxidative DNA damage in various in-vitro and in-vivo and human biopsy samples. Her PhD and postdoctoral experiences were quite different yet both productive and interlinked and were served as a background for her interdisciplinary research in environmental toxicology. When she established her own lab in University of Seoul, School of Environmental Engineering in 2002, she tried to incorporate her multidisciplinary experiences using different model systems. Her interest lies in systemic understanding of molecular mechanism of toxicity due to environmental chemicals exposure.
Her current research focus extends to the development of toxicity prediction models through computational toxicology approaches. The ultimate aim is to bridge the gap between mechanistic toxicological research and the creation of practical tools for risk assessment. To achieve this, she is actively engaged in a research project aimed at building a platform for predicting the toxicity and occurrence of environmental diseases related to chemical exposure in human health. This project leverages extensive chemical and biological databases.
Her research methodology also involves using various in vitro systems and in vivo model organisms in both human toxicology and ecotoxicology contexts. This approach naturally leads to explore the cross-species extrapolation of conserved toxic mechanisms. She investigates the toxicity of various environmental chemicals, with special attention given to nanomaterials, microplastics, and biocides. Furthermore, she is broadening her research scope to investigate the combined impacts of various chemical substances within consumer products.
While then she investigated DNA repair mechanism due to oxidative DNA damage in various in-vitro and in-vivo and human biopsy samples. Her PhD and postdoctoral experiences were quite different yet both productive and interlinked and were served as a background for her interdisciplinary research in environmental toxicology. When she established her own lab in University of Seoul, School of Environmental Engineering in 2002, she tried to incorporate her multidisciplinary experiences using different model systems. Her interest lies in systemic understanding of molecular mechanism of toxicity due to environmental chemicals exposure.
Her current research focus extends to the development of toxicity prediction models through computational toxicology approaches. The ultimate aim is to bridge the gap between mechanistic toxicological research and the creation of practical tools for risk assessment. To achieve this, she is actively engaged in a research project aimed at building a platform for predicting the toxicity and occurrence of environmental diseases related to chemical exposure in human health. This project leverages extensive chemical and biological databases.
Her research methodology also involves using various in vitro systems and in vivo model organisms in both human toxicology and ecotoxicology contexts. This approach naturally leads to explore the cross-species extrapolation of conserved toxic mechanisms. She investigates the toxicity of various environmental chemicals, with special attention given to nanomaterials, microplastics, and biocides. Furthermore, she is broadening her research scope to investigate the combined impacts of various chemical substances within consumer products.